Image of the Month: Art meets science to show tomogram of neuron-like cell and model of bacterial virus

Image of the Month: Art meets science to show tomogram of neuron-like cell and model of bacterial virus

Dr. Wah Chiu heads the lab of Electron Cryomicroscopy of Biological Nanomachines at Baylor College of Medicine. In Chiu’s lab, science not only resolves microscopic structures and relates them to their functional mechanisms, it also inspires artistic representations of those invisible worlds. The Chiu lab is dedicated to determine 3-dimensional structures of biological nanomachines by electron cryomicroscopy … Continue reading

Mouse model shows that Notch activation can drive metastatic prostate cancer

Mouse model shows that Notch activation can drive metastatic prostate cancer

Nearly 200 thousand men are diagnosed with prostate cancer every year. Most of the deaths associated with prostate cancer occur in advanced stages of the disease, which are the result of metastasis – the spreading of the tumor away from its origin. Notch signaling pathway is involved in prostate cancer and, in a paper published … Continue reading

Study shows many people use non-prescription antibiotics

Study shows many people use non-prescription antibiotics

“You may be putting your health at risk unnecessarily by using non-prescription antibiotics,” said Dr. Larissa Grigoryan, an assistant professor of family and community medicine at Baylor College of Medicine. “It is not new to report that people are using antibiotics without a prescription,” said Dr. Barbara Trautner, associate professor of infectious diseases in the … Continue reading

Gene TMEM230 suggests a novel mechanism for Parkinson’s disease

Gene TMEM230 suggests a novel mechanism for Parkinson’s disease

In the United States, Parkinson’s disease – the second most common neurodegenerative disorder without effective treatment – affects about 1 percent of the population older than 60 years of age. Most of the cases do not run in families, but the rare cases of familial Parkinson’s disease have contributed to a better understanding of the illness, as … Continue reading

Targeting B-cell malignancies with κ-specific T cells can lead to complete clinical responses

Targeting B-cell malignancies with κ-specific T cells can lead to complete clinical responses

Treating cancer with the patient’s own immune cells has been successful. In particular, treating B cell malignancies with the patients’ own immune T cells modified so that they target specific B cell markers present on malignant B cells. However, if T cells remain present in the body for prolonged periods of time, which might be … Continue reading