Image of the Month: Artist’s rendition of antigen recognition

Image of the Month: Artist’s rendition of antigen recognition

In organ transplantation the main target of the immune response is the major histocompatibility complex (MHC) which is expressed on the surface of donor cells. During an allograft transplant, donor MHC antigens are recognized by the graft recipient’s immune system triggering an immune response. Histocompatibility testing of donor and recipient tissues for MHC antigens can … Continue reading

Two Baylor College of Medicine faculty members named to the National Academy of Medicine

Two Baylor College of Medicine faculty members named to the National Academy of Medicine

Dr. Malcolm Brenner, founding director of the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist Hospital, and Dr. Cheryl Walker, founding director of the Center for Precision Environmental Health at Baylor, both renowned leaders in their respective fields, were elected to membership in the National Academy … Continue reading

Variations in gene ATAD3A can result in distinct neurological syndromes

Variations in gene ATAD3A can result in distinct neurological syndromes

Research has revealed that a group of rare neurological syndromes for which there was no cause can be the result of variations in the gene ATAD3A. The study, which appears in The American Journal of Human Genetics, shows that certain human variants of ATAD3A are associated with a lower number of mitochondria while the gene equivalents in the fruit … Continue reading

New oncogene MNX1 contributes to higher incidence of prostate cancer among African American men

New oncogene MNX1 contributes to higher incidence of prostate cancer among African American men

Genetic factors can explain, at last in part, the higher incidence of prostate cancer among African American men compared with men of other ethnic groups. A team of scientists has identified MNX1 as a new oncogene – a gene than can cause cancer – that is more active in African American prostate cancer than in … Continue reading

‘Leaky calcium’ gene linked to sudden cardiac death in epilepsy

‘Leaky calcium’ gene linked to sudden cardiac death in epilepsy

[See video below] Epilepsy is an extremely common disorder affecting people of all ages, from infants through teenagers to older adults. One of the most mysterious things about this disorder is that about 6 percent of the people with epilepsy have an unusually high incidence of sudden unexpected death. “Sudden unexpected death in epilepsy – … Continue reading