Timing exercise with muscle fuel switching could help you lose weight

Timing exercise with muscle fuel switching could help you lose weight

Skeletal muscles change their fuel preference according to a circadian rhythm. Mouse muscles, for instance, use glucose as fuel when the animals are awake and active and switch to fat when they are asleep. Understanding the molecular mechanisms that control the switch from glucose to fat can have significant repercussions in how people manage diabetes, … Continue reading

Out of sync, out of health: Social jet-lag linked to liver cancer in mice

Out of sync, out of health: Social jet-lag linked to liver cancer in mice

Our bodies are in sync with the planet’s day-and-night cycle thanks to an internal timekeeper, the circadian clock that regulates practically all the functions of the body. Recent studies have uncovered that when the internal clock goes out of sync, disease has a better chance to develop. For instance, persistent disruption of circadian rhythm in … Continue reading

Collaboration matters when looking for answers to undiagnosed diseases

Collaboration matters when looking for answers to undiagnosed diseases

It used to be that identifying genes involved in a particular disease was like finding a needle in a haystack. Nowadays, scientists still have to search through haystacks of genetic data, but advances in gene sequencing technologies and in computerized strategies to search genomic data sets with vast amounts of information have made the job … Continue reading