How infrequent seizures may lead to persistent memory loss in Alzheimer’s disease

How infrequent seizures may lead to persistent memory loss in Alzheimer’s disease

Even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models of Alzheimer’s disease; how this happens, however, has been difficult to explain. In her lab at Baylor College of Medicine, Dr. Jeannie Chin, assistant professor of neuroscience, and her colleagues have uncovered a mechanism that offers an explanation to this puzzle. “We … Continue reading

‘Silent seizures’ discovered in patients with Alzheimer’s disease

‘Silent seizures’ discovered in patients with Alzheimer’s disease

Deep in the brains of two patients with Alzheimer’s disease, the main memory structure, the hippocampus, displays episodic seizure-like electrical activity. These nonconvulsive hippocampal seizures are the first signs of ‘silent’ brain electrical network dysfunction described in patients with Alzheimer’s disease, a condition affecting more than 5 million people in the U.S. “About 10 years … Continue reading

A pill to prevent Alzheimer’s disease might someday be a reality

A pill to prevent Alzheimer’s disease might someday be a reality

Taking a pill that prevents the accumulation of toxic molecules in the brain might someday help prevent or delay Alzheimer’s disease, according to scientists at Baylor College of Medicine, Texas Children’s Hospital and Johns Hopkins University School of Medicine. The scientists took a three-pronged approach to help subdue early events that occur in the brain long before … Continue reading