Childhood condition poses risk for Parkinson’s disease later in life

Childhood condition poses risk for Parkinson’s disease later in life

In recent years, defects in the glucocerebrosidase (GBA) gene have been identified as significant risk factors for Parkinson’s disease and deficiencies in this gene also are known to cause Gaucher disease, a lysosomal storage disorder. These separate findings prompted researchers at Baylor College of Medicine to investigate whether changes in lysosome storage disorder genes in … Continue reading

Juvenile Batten disease, a problem with cellular waste management

Juvenile Batten disease, a problem with cellular waste management

Like a large dynamic city, a cell carries out many activities that generate waste. Waste needs to be disposed of properly in order for the city to continue its activities without interruption. If waste management fails, waste progressively accumulates and eventually leads to interruption and paralysis of the activities of the city. Something similar happens … Continue reading

A pill to prevent Alzheimer’s disease might someday be a reality

A pill to prevent Alzheimer’s disease might someday be a reality

Taking a pill that prevents the accumulation of toxic molecules in the brain might someday help prevent or delay Alzheimer’s disease, according to scientists at Baylor College of Medicine, Texas Children’s Hospital and Johns Hopkins University School of Medicine. The scientists took a three-pronged approach to help subdue early events that occur in the brain long before … Continue reading

Gene TMEM230 suggests a novel mechanism for Parkinson’s disease

Gene TMEM230 suggests a novel mechanism for Parkinson’s disease

In the United States, Parkinson’s disease – the second most common neurodegenerative disorder without effective treatment – affects about 1 percent of the population older than 60 years of age. Most of the cases do not run in families, but the rare cases of familial Parkinson’s disease have contributed to a better understanding of the illness, as … Continue reading